pyautogui vs UFO
Desktop automation projects compared
pyautogui automates mouse and keyboard actions in desktop applications through a shared Python interface. UFO combines Windows desktop automation with an agent framework for coordinating tasks across devices, so its scope extends from individual desktop work to multi-agent workflows.

pyautogui: Automate Mouse and Keyboard Actions in Python
PyAutoGUI lets Python scripts control the mouse and keyboard, show message boxes, and take or search screenshots across Windows, macOS, and Linux. It suits desktop workflows that can run on the primary monitor, but its development is currently inactive.

UFO: Automate Desktop Tasks Across Devices with AI Agents
UFO combines a Windows desktop agent with a framework for coordinating agents across devices and platforms. Use it for Windows automation or multi-step workflows that need task planning, device assignment, and parallel execution.
| pyautogui | UFO | |
|---|---|---|
| Language | Python | Python |
| License | BSD-3-Clause | MIT |
| Stars | 12.7k | 9.9k |
| Forks | 1.4k | 1.1k |
| Last analyzed | Oct 9, 2026 | Oct 3, 2026 |
Key differences
- pyautogui supports Windows, macOS, and Linux desktop interactions, while UFO² focuses on Windows and UFO³ Galaxy coordinates agents across devices.
- pyautogui uses mouse, keyboard, dialogs, and screenshot-based image matching; UFO combines GUI and API actions with task planning and device coordination.
- UFO Galaxy supports dependency-aware task graphs, device assignment, and parallel execution, while pyautogui focuses on direct desktop actions.
- pyautogui is licensed under BSD-3-Clause, while UFO is licensed under MIT.
- pyautogui is marked inactive, while UFO Galaxy is under active development and UFO² is presented as the stable, long-term-support option.
- Both projects use Python; UFO requires configuring an LLM provider, and Galaxy also requires device-agent and orchestration setup.
Choose pyautogui if you…
- need mouse, keyboard, dialog, or screenshot-based automation in desktop applications.
- want one interface for desktop workflows on Windows, macOS, or Linux.
- prefer a focused library for direct interactions rather than coordinating agents across devices.
Choose UFO if you…
- need Windows desktop automation that combines GUI interaction and API actions.
- want to coordinate multi-step work across device agents with task dependencies or parallel execution.
- are building device agents or workflows that use an LLM provider and orchestration configuration.
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This comparison is generated with AI from the OSRepos analyses of both projects. Always check each project's repository and documentation before choosing.